Forskolin is a potent activator of the enzyme adenylate cyclase . Adenylate cyclase is involved in the production of adenosine monophosphate, an important biochemical agent for essential metabolic processes in the body. It causes a chain reaction of biochemical processes that accelerate thermogenesis , thereby providing energy, which is burning fat deposits.
There are numerous studies that prove the effectiveness of the ForsLean . It is proven to increase the ratio of lean body mass, compared to fat stores, so you lose weight and regain a healthy balance in your body.
The effectiveness of ForsLean regarding fat burn is comparable to that of ephedrine, but unlike it , ForsLean causes no known side effects.
ForsLean ® is a registered trademark of Sabinsa Corporation and is the only Coleus forskohlii product protected by patents: US Patent # 5,804,596 and European Patent EPO977564 in weight reduction . In 2001, food suplements ForsLean receive award for best new product worldwide.
ForsLean for maintaining lean body mass The biochemical mechanism for maintaining and increasing the lean body mass is associated with the presence of cyclic adenosine monophosphate ( AMP ) .
AMP is generated in the cells of the body during normal metabolic processes. It is an intermediate compound, created in the process of extracting energy from food. The final stage of this multi-step process is the compound adenosine triphosphate ( ATP ) – a convenient form of storage and use of energy by the body.
By supporting hormonal processes, the cyclic AMP can regulate thermogenic response of the body to the food, increases the main metabolic levels of the body and increases the use of the fat ( because it order to trigger thermogenesis it uses fatty acids from adipose tissue and / or by the food)
What is lean body mass?
Lean body mass is composed of muscle , vital organs, bone, bone marrow, connective tissue and the body water . Relationship between lean body mass and body fat determines not only the aesthetic appearance of the body , but also indicates good health , health status and susceptibility to disease and the risk of premature death. Body mass index (BMI ) is a reliable indicator of health condition of the body .
You can calculate your BMI using the following formula weight (in kg. )
BMI: ————————- (Height in meters ) 2
The rate of BMI is between 18 and 25 kg/m2.
Rates above 25 indicate overweight.
Rates above 30 refer to obesity.
Mechanism of action of ForsLean ®
ForsLean changes the ratio of lean muscle mass and fat deposits in the body. This improves the overall health. The mechanism of action of ForsLean is very clear. Forskolin , the active ingredient of ForsLean is a powerful activator of the enzyme adenylate cyclase . Forskolin and the destruction of fat tissue Forsolin | boosts Enzyme adenylate ziklaza | increases Levels of cyclic AMP | activates Protein Kinasa | phosphorylation Active form of hormone – sensitive lipase stimulates —– —-> release of fatty acid from fatty tissues in the body As mentioned, forskolin is known as a compound with multiple biological activities due to its ability to stimulate adenylate cyclase and cyclic AMP levels.
Phytochemistry of Forskolin forskohlin (7ß-acetoxy- 8 ,13-epoxy-1a, 6bß, 9a-trihydroxylabd- 14 -en11-one) diterpenoid chemical compound that directly activates adenylate ziklaza. Also other four smaller diterpenoids are contained in root of Koleus Forskolii – deatsitilforskolin 9 – deoksiforskolin, 1,9 – deoksiforskolin, 1,9 – dideoxy -7- deatsitilforskolin; For best results in weight reduction , we recommend the combination with Liquid Off. ForsLean is part of the “Weight Management” program created by Detox Center.
Product series “Weight Management” focuses on the problem of weight control. It includes dietary supplements and procedures, included in a a complex approach to this serious health and cosmetic problem . U.S. Patent 5,804,596 European Patent EPO977564